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Postmortem investigations of neuronal and glial cells in MDD revealed neuronal atrophy, neuronal shrinkage, an increased density of microglia, a reduction in astroglial cells, impaired neurogenesis, a decrease in hippocampal volume, a decreased density of total glia and oligodendrocytes in the amygdala, and a depletion of oligodendrocytes [1]

This mechanism was also confirmed in subsequent studies

Adv Healthc Mater 2020;9(20):e2000605

We observed much more severe inflammation in the kidney of the WT mice infected by the S

doi: 10.1016/j.pbb.2021.173243 Pubmed Abstract CrossRef Google Scholar View reference in article 51 GriffinSMPickardMROrmeRPHawkinsCPFrickerRA